Cefpirome sulfate CAS 98753-19-6

Product Name: Cefpirome sulfate
Synonyms: 1-[[(6r,7r)-7-[[(2z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5h-cyclopenta[b]pyridinium sulfate;CEFPIROME SULFATE;Keitin);Cefquinome base;CefpiromeSulfate3%;1-(((6R,7R)-7-((Z)-2-(2-AMinothiazol-4-yl)-2-(MethoxyiMino)acetaMido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)Methyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-1-iuM hydrogensulfate;CEFPIROME SULFATE USP 27;(6r-rboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-
CAS: 98753-19-6
MF: C22H24N6O9S3
MW: 612.66
EINECS: 685-392-7
Product Categories: Antibacterial;Miscellaneous;cephalosporins antibiotics;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Pharmaceutical raw material;api
Mol File: 98753-19-6.mol
Cefpirome sulfate Structure
Cefpirome sulfate Chemical Properties
Melting point 198-2020C (dec)
alpha 25D -4.7° (c = 5 in H2O)
RTECS UW8970000
storage temp. Store at 0-5°C
solubility Soluble in DMSO
λmax 265nm(Buffer)(lit.)
Merck 14,1940
CAS DataBase Reference 98753-19-6(CAS DataBase Reference)
Safety Information
MSDS Information
Cefpirome sulfate Usage And Synthesis
Description Cefpirome sulfate is a new injectable cephalosporin indicated for the treatment of severe urinary and respiratory tract infections, including septicemia and nosocomial infections. Cefpirome sulfate is reported to be the first true fourth-generation cephalosporin due to its similar activities to third-generation antibiotics against Gram-positive bacteria and to first-generation antibiotics against Gram-negative bacteria. Its efficacy against P.aeruginosa is comparable to ceftazidime. The broad spectrum of activity includes Klebsiella, methicillin-sensitive staphylococci, penicillin-resistant pneumococci, E.coli which generates extended-spectrum beta-lactamases and multi-resistant organisms such as Citrobacter, Enterobacter and Serratia.
Chemical Properties White Crystalline Powder
Originator Hoechst AG (Germany)
Uses Fourth generation cephalosporin antibiotic
Brand name Cefrom (Hoechst-Roussel).