Doxycycline CAS 564-25-0

Product Name: Doxycycline
Synonyms: (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide;Doxycyclin hyclate;Doxycycline Base & Hyclate;Doxycycline (base and/or unspecified salts);(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;DOXYCYCLINE, ANHYDROUS;6- Deoxy-5-hydroxytetracycline, 6-Deoxyoxytetracycline, Doxytetracycline, GS 3065, HydraMycin, MedeoMycin, VibraMycin;(4S,4aR,5S,5aR,6R,12aS)- 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro -3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hyclate
CAS: 564-25-0
MF: C22H24N2O8
MW: 444.44
EINECS: 209-271-1
Product Categories: FUNGICIDE;Intermediates & Fine Chemicals;-;Pharmaceuticals
Melting point 206-209°C (dec.)
Boiling point 554.44°C (rough estimate)
density 1.3809 (rough estimate)
Uses tetracycline antibiotics
Uses Doxycycline is a semi-synthetic tetracycline prepared by hydrogenolysis of oxytetracycline to remove the 6-hydroxy group. Although the synthesis was reported in 1958, it was not released for use until 1967. Doxycycline, together with minocycline, is regarded as a `third generation` tetracycline largely replacing the analogues and pro-drugs produced in the early 1960s for mainstream antibiotic applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Doxycycline has been extensively cited in the literature with over 10,000 references.